As a result, a higher expression of CYP4X1 was observed in normal tissues compared to cancer tissues in esophageal carcinoma (ELCA), glioblastoma multiforme (GBM), head and neck squamous cell carcinoma (HNSC), kidney cancer (KIRC; kidney renal clear cell carcinoma, KIRP; kidney renal papillary cell carcinoma), and thyroid carcinoma (THCA). This evidence concerns the gene CYP4X1 and cancer.