Figure 2 shows the analysis of expression of ECM proteins fibronectin (FN) and collagen type 1 (COL1A1) in the renal samples from the different experimental groups. In WT FA, the expressions of FN (Figure 2A) and COL1A1 (Figure 2B) were increased compared with WT CT. However, the increase in both proteins was prevented in cKD-ILK FA. Figure 2C shows the histopathological analysis of ECM interstitial deposition on kidney sections after FA treatments by using Sirius red staining and the analysis of red intensity per area photographed [5,6]. This evidence concerns the gene COL1A1 and chronic kidney disease.