CCL5 and rheumatoid arthritis: Elevated levels of CCL5/RANTES have been demonstrated to contribute to the pathogenesis and progression of autoimmune disorders, including bronchial asthma, rheumatoid arthritis, systemic lupus erythematosus, and Addison’s disease [62,63,64].Although the inflammatory response of the body represents one of the body’s defense mechanisms against cancerous growths, a chronically sustained inflammatory state can paradoxically promote their development.