FCGR2B and systemic lupus erythematosus: These genotype and allele frequencies of FcγRIIb are associated with incidence of leukopenia, rash, mucosal ulcer, arthritis, and thrombocytopenia in SLE patients, these parameters are considered in the SLE Disease Activity Index (SLEDAI), the main clinimetric tool to evaluate the remission and low disease states [80].