ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: In this view, we evaluated WBC counts and BCR::ABL1 quantitative level either at diagnosis and on day 7 and day 14 of treatment in a cohort of patients with newly diagnosed BCR::ABL1-positive CP-CML treated with or without cytoreduction with HU before frontline treatment with TKIs.