SNAP25, SYN2, SYP, SYT1, APP, SNCA, BDNF, GFAP, VAMP2, MAPT, and SLC17A7 are among the top 50 genes identified as potential targets for early-stage AD [40,41,42,43,44,45,46]. The gene discussed is VAMP2; the disease is Alzheimer disease.