KEGG functional enrichment analysis showed that the PI3K-Akt signaling pathway [61], MAPK signaling pathway [62], AGE-RAGE signaling pathway [63], which are closely related to diabetes mellitus, and the FoxO signaling pathway are significantly enriched [64], and these pathways have been shown by many studies to play an important role in antidiabetes. This evidence concerns the gene RENBP and diabetes mellitus.