Researchers have found that dietary polysaccharides from Polygonatum sibiricum can reduce the insulin resistance index, increase the OGTT and serum insulin levels, lower the free fatty acid content to improve lipid metabolism, and reduce the glycosylated serum protein content to enhance glucose metabolism in T2DM mice, leading to a decrease in blood sugar [46]. The gene discussed is INS; the disease is type 2 diabetes mellitus.