Overexpression of CD1c, CD2, CD3, CD4, CD11c, CD14, CD20, CD44, CD56, CD105, CD146, and CD209 was observed in patients with LCa, while CD24, CD31, and CD40 were not overexpressed in patients with LCa, but were found to be associated with nodal involvement. The gene discussed is ENG; the disease is Leber congenital amaurosis.