NPPB and hydrops fetalis: A global rank endpoint in which all participants, regardless of treatment assignment, were ranked across three hierarchical tiers: Tier 1 = time to death or urgent heart transplantation or implantation of a ventricular assist device (VAD).Tier 2 = time to non-fatal HF requiring IV vasoactive therapy.Tier 3 = time-averaged proportional change in NT-proBNP from baseline to week 14, each multiplied by the number of elapsed times in weeks, divided by the total number of 14 weeks of observation from baseline to 14 weeks.