CDKN2A and meningioma: Additionally, combining a genome-wide DNA methylation analysis, mRNA expression and copy number alterations, four stable molecular groups (MGs) of meningiomas were invented with MG3 and MG4, including TERTp mutations and homozygous CDKN2A/B deletion, as well as novel somatic mutation in KDM6A, CHD2 and PTEN [100].