IDH1 and central nervous system cancer: Recently, the combined evaluation of DCE-MRI and DKI was proposed to facilitate the prediction of high-grade (HGG) vs. low-grade gliomas (LGG), IDH1/2 wildtype vs. IDH1/2 mutant gliomas, and high-grade oligodendroglial vs. high-grade astrocytic gliomas [20].