The objective of this study was to quantitatively compare the diagnostic performance of DCE-MRI and DKI in molecular subtype identification according to the WHO 2021 classification of CNS tumors, which divides adult-type diffuse gliomas into glioblastomas, IDH wildtype; astrocytomas, IDH mutant; and oligodendrogliomas, IDH mutant and 1p/19q-codeleted [2,21,22]. This evidence concerns the gene IDH1 and glioblastoma.