LPL and Paraproteinemia: Two different subtypes of LPL are recognized: (i) Waldenström macroglobulinemia (WM) type, which accounts for 95% of the cases and is characterized by the association with IgM paraproteinemia; and (ii) non-WM type, a rare subtype representing 5% of LPL, which can be divided into cases with IgG or IgA paraproteinemia, non-secretory LPL, and IgM LPL without bone marrow involvement [8,37].