NECTIN4 and ovarian carcinoma: To determine whether the inhibition of cell adhesion could be used as a novel strategy to increase chemosensitivity in ovarian cancer treatment, we used the Nectin-4 peptide N4-P10 to block spheroid formation in cell lines and cells isolated from ovarian cancer patient ascites and tested them for the cytotoxicity of the platinum chemotherapeutic agent, cisplatin.