Common heritable cancer predisposition syndromes associated with sarcomas include Familial Adenomatous Polyposis (FAP), Carney–Stratakis, Hereditary Retinoblastoma (RB1), Li–Fraumeni Syndrome, Neurofibromatosis (NF1), Werner Syndrome, Tuberous Sclerosis, Hereditary Leiomyomatosis and renal cancer (HLRCC) [13], Ollier disease, and Maffucci’s syndrome [14]. This evidence concerns the gene NF1 and tuberous sclerosis.