CD274 and neoplasm: Apart from histopathological types and sub-types, AI can also determine the PD-L1 status of the tumor with an accuracy and specificity of over 95% and an AUC of 0.8 [289,301,355], while the concordance between pathologists when scoring the PD-L1 status of a tumor with the assistance of AI was increased by between 4% and 9%, when compared to scoring without AI assistance [291,356,357]; although these results mainly concern tumors with cutoff points in PD-L1 expression of up to 49% and worsen when PD-L1 expression is 50% or higher [358].