FCGRT and cancer: While SPEDOX-6 can achieve high antitumor efficacy on TNBC (MDA-MB-231) with a medium FcRn expression level of 18 TPM [10], it is more potent against STS (HT-1080) xenografts with the lowest FcRn expression level at <2 TPM among all cancer cell lines in the database [45].