MPAL with KMT2A usually has a B/myeloid immunophenotype (an example case of MPAL with KMT2A::USP2 fusion, B/myeloid (bilineal, pattern 1b, in Figure 7)), although other immunophenotypic variants, including rare cases of AUL and T/myeloid MPAL, have been reported [14,15,16]. Here, USP2 is linked to mixed phenotype acute leukemia.