This entity compromised 7% (2/29) of the total MPAL cases in a study by Xiao et al., with gene alterations in PHF6, NOTCH (NOTCH1 and FBXW7), and JAK/STAT pathways [28], and a molecular profile that overlapped with that in B/T MPAL and ETP-ALL. This evidence concerns the gene NOTCH1 and mixed phenotype acute leukemia.