Of interest, data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2020, with different definitions of SLD applying, construct a biochemical phenotype of patients at risk for NAFLD/MAFLD, who present with lower iron, higher ferritin, and lower transferrin saturation levels, whereas the risk for hepatic fibrosis was higher for the same biochemical profile patients from the USA [68,69,70]. The gene discussed is TF; the disease is metabolic dysfunction-associated steatotic liver disease.