Protein expression levels of known melanoma markers [36], such as MITF, MLANA, PMEL, TYR, and SOX10, had the lowest expression in EC-Mit samples (ANOVA, FDR < 6 × 10−4) and had a significantly lower expression in the EC-like subtypes when compared to the Mit-like subtypes (Figure 2A). This evidence concerns the gene PMEL and melanoma.