STAT1 and infection: By excluding infection-related episodes and relapse status, “IFN”-related single genes IFI44 (M8.3 “type I interferon”), GPB1, and STAT-1 (M10.1 “interferon”) were confirmed significant, while the whole “IFN” module 10.1 (composed by “GPB1”, “IFI35”, “STAT-1”, and “ZBP1” genes) was not confirmed, suggesting that IFI35 and ZBP1 genes rather reflect a microbial- or post-relapse-induced IFN expression.