TXNIP and graft versus host disease: The “protein synthesis” module M10.2 (HBB, RPS12, and OAZ1) CTSS gene (cathepsin S, associated with MHC class II antigen presentation linked to the “inflammation” module) and TXNIP gene (thioredoxin interacting protein, regulator of cellular redox signaling linked to “neutrophils”) appeared consistently in all patients, including non-GVHD patients (Figure 3B, first two plots), and some pre-transplantation samples.