There was a statistically significant correlation between tumor grade and CXCR4 expression: the median (Q1–Q3) 68Ga-Pentixafor PET/CT SUVmax was 5.32 (4.24–6.96) for Bloom Richardson grade II and 7.40 (6.77–9.57) for grade III (p = 0.002) as shown graphically in Figure 2. This evidence concerns the gene CXCR4 and neoplasm.