MAPT and Alzheimer disease: Notably, RNA-inducedLLPS exhibited distinct phase behavior compared to phosphorylation-inducedLLPS, highlighting the importance of RNA in modulating tau’scondensation and aggregation tendencies within cellular environments.Furthermore, p-tau SC can induce tauRD aggregation at the nuclearenvelope, as observed in AD brain sections, implying that p-tau SCmight play a crucial role in AD pathogenesis.