Among TSGs, ATM was associated at p < 1 × 10−4 for breast, prostate, pancreatic, and esophagus cancer; BRCA2 was associated at p < 1 × 10−4 for breast, prostate, and ovarian cancer; and MSH6, MSH2, and MLH1 were associated at p < 1 × 10−4 for bowel and endometrial cancer. The gene discussed is MSH2; the disease is endometrial cancer.