CD34 and myelodysplastic syndrome: Given the central role of CD34+ cells in hematopoiesis, this study specifically focuses on gene expression changes in CD34+ hematopoietic stem cells from MDS patients [13,14,15].Although the etiology of MDS remains incompletely understood, the rapid development of advanced technologies such as high-throughput sequencing has enabled the identification of an increasing number of MDS-related genetic mutations.