ELANE and systemic lupus erythematosus: For the high-expression group of ELANE, biological processes such as antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptides, defense response to Gram-negative bacterium, and related KEGG pathways like cell cycle, DNA replication, hematopoietic cell lineage, oocyte meiosis, and systemic lupus erythematosus were significantly enriched.