confirmed the roles of the LAT1 heterodimer (SLC7A5 and SLC3A2), a remnant of erythropoiesis with SNPs significantly associated with RBC kynurenine levels [68], and y+LAT2 heterodimer (SLC7A6 and SLC3A2), initially identified via RBCs of individuals with Lysinuric Protein Intolerance [69, 70], in driving the exchange of amino acids across the membrane. The gene discussed is SLC3A2; the disease is lysinuric protein intolerance.