COL7A1 and recessive dystrophic epidermolysis bullosa inversa: Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic skin fragility disorder caused by loss‐of‐function variants in the COL7A1 gene encoding type VII collagen (C7), which is the main component forming anchoring fibrils at the dermal‐epidermal junction.[1, 2] These anchoring fibrils provide structural stability, and pathogenic variants in COL7A1 disrupt fibril assembly, leading to weakened skin integrity.