Atx2 is associated with a range of human diseases, including Parkinson’s disease (PD), spinocerebellar ataxia (SCA1, SCA2, MJD), amyotrophic lateral sclerosis (ALS), primary open-angle glaucoma (POAG), and obesity/type I diabetes [14]. This evidence concerns the gene ATXN2 and type 1 diabetes mellitus.