When the cohorts were stratified for BMI ≤ 29.9 kg/m2 and normal HOMA-IR (≤1.9), FGFR1, VEGF-D, IGF1, and IGF-1sR differed, suggesting that these factors are more likely to be inherently different in PCOS rather than an epiphenomenon of an associated PCOS feature such as BMI or IR. Here, IGF1 is linked to polycystic ovary syndrome.