This reduction in IL-11 expression in the eutopic endometrium, likely resulting from progesterone resistance and altered PKA signaling, may contribute to endometriosis-associated infertility through multiple mechanisms: impaired decidualization, defective implantation, compromised placentation, altered Natural Killer cell differentiation, and decreased decidual cell survival [75,76,77,78,79,80,81]. Here, IL11 is linked to endometriosis.