Similarly, Barragán et al. reported undetectable IGFBP1 secretion in endometrial mesenchymal stem cells (eMSCs) and endometrial stromal fibroblasts progenitors (eSFs) from endometriosis patients following a 14-day E2 and P4 treatment, contrasting with significant IGFBP1 secretion in cells derived from women without endometriosis [19]. The gene discussed is IGFBP1; the disease is endometriosis.