Another study demonstrated that ER-Golgi transport can act as a regulator of hypertrophic growth in cardiomyocytes, as the overexpression of RAB1, which governs the transport of the transcription factor angiotensin II (AngII) receptor from ER to Golgi, enhancing cell growth in neonatal cardiomyocytes as well as pathological cardiac hypertrophy in mice [211,212]. The gene discussed is AGT; the disease is cardiac hypertrophy.