Bioluminescence imaging showed that after three treatments with erastin and ML385, the tumour volume of the IL4I1 overexpression group was larger compared with that of the control group, and that the tumour volume of the IL4I1 overexpression group treated with both erastin and ML385 was smaller compared with that of the IL4I1 overexpression group only treated with erastin (Figure 8B,C). The gene discussed is IL4I1; the disease is neoplasm.