Interestingly, a recent study found that CAFs in oral squamous cell carcinoma (OSCC) exhibit higher ITGB2 expression compared to matched normal fibroblasts.[44] Additionally, conditioned media from ITGB2‐expressing CAFs was more effective in promoting OSCC cell proliferation than that from wild‐type controls. Here, ITGB2 is linked to oral cavity squamous cell carcinoma.