KLK3 and cancer: Figure 5A highlights that terms such as prostate cancer, mortality, prostate-specific antigen, risk, and radical prostatectomy are among the most frequently occurring keywords, representing the hot topics in this field over the past decade. Clustering these keywords revealed that they primarily fall into three clusters: #0 prostate-specific antigen, #1 androgen receptor, and #2 cancer screening (Figure 5B).