SATB1 and colorectal cancer: further confirmed that SATB1 induced β-catenin translocated into the nuclear and promotes colorectal cancer tumorigenesis by in vitro and in vivo experiments (39).This shift is associated with reduced membrane-bound β-catenin, increased EMT markers (e.g., Vimentin), and decreased CDH1 and CK20 levels, highlighting SATB1’s role in promoting metastasis (32).