CENP-H overexpression has been positively associated with poor overall survival (OS) in patients with RCC, GC, nasopharyngeal cancer, EC, LC, cervical cancer, esophageal squamous cell carcinoma (ESCC), liver cancer, BC, and tongue cancer (7, 9, 11–13, 15–17, 20–22), and is significantly associated with short relapse-free survival in patients with hypopharyngeal squamous cell carcinoma (10). The gene discussed is CENPH; the disease is laryngotracheoesophageal cleft.