CENP-H overexpression has also been positively correlated with pathological stage, T stage, and lymph node metastasis of patients with cancer, and is significantly correlated with pathological stage and T stage in patients with RCC, GC, hypopharyngeal squamous cell carcinoma, nasopharyngeal carcinoma, EC, LC, cervical cancer, ESCC, liver cancer, OSCC, BC, and tongue carcinoma. The gene discussed is CENPH; the disease is esophageal squamous cell carcinoma.