Exercise increased Cpt1a in NAFLD, the rate-limiting enzyme for beta-oxidation, from normal (Almeida et al., 2013[5]; Wang et al., 2017[154]) and reduced its baseline levels (Evangelista et al., 2015[35]; Ok et al., 2018[111]; Pereira et al., 2019[117]; Yan et al., 2018[164]). Here, CPT1A is linked to metabolic dysfunction-associated steatotic liver disease.