Our mIF assay (panel 4, Supplementary Tables S2, S3) (Figure 6A, Supplementary Figure S4C) showed increased prevalence (both as frequencies and cell density) of CD11chi/dimTbethi B cells in SLE follicular (CD19-dense areas) and especially extrafollicular areas (p<0,05), compared to control LNs, regardless the gender of SLE individuals (Figure 6B). Here, CD19 is linked to systemic lupus erythematosus.