Similar analyses were also conducted for significantly down-regulated DEGs identified when comparing DLBCL and CLL samples, yielding 90 enriched GO-BP terms including the immune response, cellular response to TNF and IFN-γ, positive regulation of ERK1 and ERK2 signaling pathways, and lymphocyte chemotaxis pathways. This evidence concerns the gene TNF and B-cell chronic lymphocytic leukemia.