CD8A and cholangiocarcinoma: From reading the literature published so far studying cholangiocarcinoma and T lymphocytes, we can assume that regardless of CCA subtype, CD8+ and CD4+ T cells are mainly located in the peri-tumor area, and Foxp3+ T cells mainly infiltrate in the tumor center, but for some The contrary reports may be related to different sample sizes and research methods, so more research is needed to confirm.