However, our findings were consistent with the results of a study involving 1653 CRC patients, in which high expression of Ki67 was associated with good clinical outcomes in CRC patients and with good treatment outcomes in patients receiving adjuvant chemotherapy for colon cancer (45, 55) Notably, our verification results showed that the low expression group of Ki67 had a longer OS, while the expression of MKI67 in the TCGA database did not affect the survival of BRCA. The gene discussed is MKI67; the disease is malignant colon neoplasm.