IL1A and male infertility: Another 6 CIPs were identified as having potentially significant relationships impacting male infertility, including 3 beneficial: Monocyte chemoattractant protein-1 (MCP1) (95% CI: 1.0956 to 1.7563, p=0.0066), Cystatin D (CST5) (95% CI: 1.0403 to 1.6323, p=0.0213), and Interleukin-2 (IL2) (95% CI: 1.0198 to 2.1619, p=0.0392) and 3 deleterious: Interleukin-1-alpha (IL1A) (95% CI: 0.4252 to 0.9275, p=0.0194), C-C motif chemokine 25 (CCL25) (95% CI: 0.7241 to 0.9867, p=0.0332), and TNF-related activation-induced cytokine (TRANCE) (95% CI: 0.6154 to 0.9888, p=0.0401).