LRFN4 and neoplasm: Liu et al. have reported that the in clinical gastric cancer tissues, LRFN4 expression was elevated in tumor cells and fibroblasts, and the overexpress of LRFN4 was substantially linked with tumor invasive features, and the gastric cancer patients with high LRFN4 expression had poor prognosis (Liu et al., 2019a).