FTH1 and ischemia: Resveratrol mainly exists in veratrum pilosa, knotweed, grape, and other plants, and it has immune regulatory, anti-oxidant, anti-inflammatory, myocardial protective, and other biological properties.60, 61, 62, 63 Researchers have found that in oxygen–glucose deprivation/reoxygenation-induced H9c2 cells and ischemia–reperfusion rats, resveratrol reduced ferroptosis, decreased TFR1 expression, and elevated the expression of FTH1 (ferritin heavy chain 1) and GPX4.