A nonsynonymous frameshift insertion in DnaJ Heat Shock Protein Family (Hsp40) Member B7 (DNAJB7) was found to be under selection in central MI populations, and two nonsynonymous variants were identified in ID3 and NCK Associated Protein 5 Like (NCKAP5L) for southern MI populations. Here, NCKAP5L is linked to myocardial infarction.