SLC6A1 and hereditary elliptocytosis: By contrast, HE GAT1 KO mice are reported to show no overt behavioral alterations (Chiu et al. 2005), despite the presence of intermittent epileptiform activity on EEG (Lindquist et al. 2021), and the fact that human carriers of single GAT1 mutations exhibit severe symptoms (Goodspeed et al. 2023).