After adjusting for confounding factors, including age, HbA1c, fasting glucose, albumin, creatinine, triglycerides, cholesterol, races, educational levels, alcohol consumption, CKD, hypertension, the relationship between the TyG index and its related parameters with the likelihood for TB infection was found to be approximately linear (all p values for non-linearity > 0.05). This evidence concerns the gene ALB and chronic kidney disease.