Through a search of the Gene Expression Profiling Interactive Analysis (GEPIA, http://gepia.cancer-pku.cn/) database, we demonstrated that the expression of NUTM1 is decreased in testicular germ cell tumors (TGCT), while PTPRD shows marked downregulation in kidney renal clear cell carcinoma (KIRC) compared with normal tissues (Fig. 5A-B). The gene discussed is NUTM1; the disease is testicular germ cell tumor.