The presence of one or two alleles (with the value 0.5 in the x-axis being linked to the presence of one allele and value 1 to the presence of two alleles) of the rs429358 SNP, which is associated with the Apolipoprotein E (ApoE) gene23, almost linearly increased the individual’s probability of being classified as an AD rather than an MCI patient, as shown in Fig. 4b. Here, APOE is linked to Alzheimer disease.