To further validate the prognostic value of these genes in breast cancer, we conducted COX regression analysis and found that MGAT4EP exhibited predictive performance for breast cancer prognosis with an AUC > 0.6, specifically AUC = 0.673 (Figure 1b), while TP53AIP1 showed a lower predictive ability (Supplementary Figure S1a). The gene discussed is TP53AIP1; the disease is breast carcinoma.